New MAL Blood Group System Identified, Revealing Genetic Basis of Rare Blood Types

Scientists have identified a new blood group system called MAL, which includes the AnWj antigen. This discovery, led by Dr. Louise Tilley and her team at NHS Blood and Transplant, resolves a decades-old mystery and facilitates the creation of new genotyping tests. Over 99.9% of individuals are AnWj-positive, but those who are AnWj-negative could face serious transfusion reactions.


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